SEROPREVALENCE OF HEPATITIS B AND C VIRUS IN VOLUNTARY BLOOD DONORS AT TERTIARY CARE HOSPITAL OF BANNU, PAKISTAN
Abstract
Background: After the introduction of blood banks, blood transfusion has become
very common which can transmit many infections including hepatitis B and C viral
infections. This study is aimed determine the seroprevalance of hepatitis B and C
virus in voluntary un-paid blood donors and to make recommendations for safe blood
transfusions.
Methodology: This retrospective chart review study was conducted at Khalifa Gul Nawaz Teaching Hospital (KGNTH), Bannu, between 1st April 2011 and 31st March 2015. A total of 3650 voluntary blood donors were included in the study. All the blood samples were screened for hepatitis B surface antigen (HBSAg) and anti hepatitis C virus (AntiHCV) antibodies by enzyme linked immuno-sorbent assay (ELISA) before accepting the blood donation. Ages of donors ranged from 18-52 years. Males outnumbered the females.
Results: Out of 3650 donors 61 (1.67%) were positive for HBSAg and 38 (1.04%) were positive for Anti-HCV.
Conclusion: Although the seroprevalence of hepatitis B and C virus was low in this study but still it is of utmost importance to continue screening donated blood with highly sensitive and specific tests to ensure the safety of blood for recipient.
References
Nwokeukwu IH, Nwabuko CO, Chuku A, Ajuogu E, Dorathy OA. Prevalence of human immunodeficiency virus, hepati-tis B virus, hepatitis C virus and syphilis in blood donors in a tertiary health facility in south eastern Nigeria. Hematol Leuk. 2014;2(4):1-4.
Shah SMA, Khattak IU, Ali A, Tariq M. Seropositivity fo hep-atitis B and C in voluntary blood donors. J Ayub Med Coll Abbottabad 2010;22(3):149-51.
Waheed U, Zaheer HA, Naseem L, Hasn K. Study of hepa-titis B and C virus seropositivity in healthy blood donors. Ann Pak Inst Med Sci. 2009;5(4):233-6.
Viet L, Lan NTN, Ty PX, Bjorkvoll B, Hoel H, Gutteberg T et al. Prevalence of hepatitis B and hepatitis C virus infec-tions in potential blood donors in rural Vietnam. Indian J Med Res. 2012;136:74-81.
Nazar H, Nadia N, Shazia N, Zulfiqar A, Farhat A. Prev-alence of hepatitis B and hepatitis C in blood donors of Karachi. Biomedica. 2008;24:116-7.
Ali Sa, Donahue RMJ, Qureshi H, Vemunda SH. Hepatitis B and Hepatitis C in Pakistan:Prevalance and risk factors. Int J Infect Dis. 2009;13(1):9-19.
Rodenas JG, Becasen LC, Que ER. The prevalence of HB-SAg (+) and Anti HCV (+) among healthy blood donors at East Avenue Medical Center, Quezon city. Phil J of Gastro-entrology. 2006;2:64-70.
El Beltagy KE, Al Balawi IA, Almuneef M, Memish ZA. Prev-alence of hepatitis B virus markers among blood donors in a tertiary hospital at Tabuk, Northwestren Saudi Arabia. Int J Infect Dis. 2008;12(5):495-9.
Butsashvili M, Tsertsvadze T, McNutt LA, Kamkamidze G, Gvetadze R, Badridze N. prevalence of hepatitis B, hep-atitis C, syphilis and HIV in Georgian blood donors. Eur J Epidemiol. 2001;17:693-5.
El-Gelany AH, El-Fedawy S. Blood born infections among student voluntary blood donors in Mansoura University, Egypt. East Mediterr Health J. 2006;12:742-8.
Khattak MF, Salamat N, Bhatti FA, Qureshi TZ. Seropreva-lence of hepatitis B, C and HIV in blood donors in Northren Pakistan. J Pak Med Assoc. 2002;52(9):398-402.
Ijaz AU. Hepatitis B and hepatitis C in blood donors; Anal-ysis of two years data. Annals. 2007;13(1):59-6
Begga PK, Singh SP. Seroprevalence of hepatitis C antibod-ies in healthy blood donors--a prospective study. Indian J Pathol Microbiol. 2007;50(2):429-32.
Afsar I, Gungor S, Sener AG, Yurtsever SG. The prevalence of HBV, HCV and HIV infections among blood donors in LZmir, Turkey. Indian J Med Microbiol. 2008;26:288-9.
Ayoola AE, Tobaigy MS, Gadour MO, Ahmad BS, Hamza MK. The decline of HBV viral infection in South-Westren Saudi Arabia. Saudi Medical J. 2003;24:991-5.
Bangash MH, Bangash TH, Alam S. Prevalence of hepatitis B and hepatitis C among healthy blood donors at Kurram Agency. JPMI 2009;23(2):140-5.
Al-Gani FA. Prevalence of HBV, HCV and HIV-1, 2 infec-tions among blood donors in Prince Rashed Ben Al-Hassan Hospital in North Region of Jordan. Int J Biol Med Res. 2011;2(4):912-6.
Mehmood MA, Khawar S, Anjum H, Ahmad SM, Rafiq S, Nazir I. Prevalence of hepatitis B, C and HIV infection in blood donors of Multan region. Ann King Edward Med Coll. 2004;10(4):459-61.
Dayan S, Tekin A, Tekin R, Dal T, Hoşoğlu S, Yazgan UC et al. HBsAg, anti-HCV, anti-HIV 1/2 and syphilis seropreva-lence in healthy voluntary blood donors in southeastern Anatolia J Infect Dev Ctries. 2013; 7(9):665-9.
Sonia, Rajesh K, Amarjit K. Prevalence of Hepatitis C Virus Seropositivity among Blood Donors in a Tertiary Care Hos-pital Gupta. Int Res J Medical Sci. 2015;3(2):22-4.
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