Objective: There is no data showing which gender is predominantly affected by ce-
liac disease (CD) available from Pakistan. This study was aimed to determine which
gender is more affected by celiac disease.
Material and methods:
This cross sectional study was performed at Fatima Memo-rial Hospital, Lahore-Pakistan. 121 patients were recruited in the study according
to the inclusion and exclusion criteria. Every patient went through upper gastro-
intestinal endoscopy, as duodenal biopsy is the gold standard of the diagnosis.
Histopathological evaluation was done according to Modified Marsh classifica-
Out of 121 patients, 14 were diagnosed to have celiac disease. Out of
14 patients 11 (78.5%) were females and 3 (21.5%) were males.
Females are predominantly associated with celiac disease with female to male ratio of3.6:1.
Catassi C, Fasano A. Celiac disease diagnosis: simple rules are better than complicated alogrithms.Am J Med 2010; 123(8):691-3.
Licata A. Serology in adults with celiac disease: limited accuracy in patients with mild histological lesions. Intern Emerg Med 2011; 7(4):337-42.
Mustalahti K, Catassi C, Reunanen A, Fabiani E, Heier M, McMillan S et al. The prevalence of celiac disease in Eu-rope: results of a centralized, international mass screen-ing project. Ann Med 2010; 42(8): 587-95.
Van der Windt DA. Diagnostic testing for celiac disease among patients with abdominal symptoms: a systematic review. JAMA 2010; 303(17):1738-46.
Ciacci C, Cirillo M, Sollazzo R, Savino G, Sabbatini F, Maz-zacca G. Gender and clinical presentation in adult celiac disease. Scand J Gastroenterol 1995; 30(11):1077-81.
Murray J, Van C, Plevak F, Dierkhising A, Zinsmeister R, Melton J. Trends in the identification and clinical features of celiac disease in a North American community, 1950-2001. ClinGastroenterolHepatol2003; 1(1):19-27.