Background: The circulation of blood in the bones is necessary for osteogenesis, maintenance of bone vitality, bone growth and repair of fracture and other injuries. The nutrient foramina are holes that allow blood vessels to pass through the bone cortex.
Methodology: This was a cross-sectional study conducted from February 2013- Sep-tember 2013, at the department of Anatomy, Ayub Medical College (Osteology Sec-tion), Abbottabad and Department of Anatomy, Khyber Medical College (Osteology Section), Peshawar with the due consents of the heads of the institutions. The aim of the present study was to observe the diaphyseal nutrient foramina in the human upper and lower limb long bones. This study was done on 180 human long bones, consisting of humerii, radii, ulnae of upper limb and femora, tibiae and fibulae of lower limb bones with 30 bones each..
Results: Our study was conducted on 180 long bones of upper and lower limbs. More than 80% of the long bones of upper and lower limbs had single nutrient foramen, whereas occurrence of double nutrient foramina was around 18%. Direction of nutrient foramina in case of humerus was distal, where as in cases of radius and ulna direction was proximal. In case of femur direction of nutrient foramina was proximal where as in cases of tibia and fibula most of nutrient foramina were directed distally.
Conclusion: The present study has provided additional information on the morphology, foramina index and topography of the nutrient foramina in the upper and lower limb long bones. The anatomical data is important to the clinicians as the micro-vascular bone transfer is becoming popular.
Grabowski P. Physiology of bone. Endocrine develop-ment. 2009;16:32-48. Epub 2009/06/06.
Al-Motabagani M. The arterial architecture of the human femoral diaphysis. J Anat Soc India. 2002;51:27-31.
Jonsson A, Gustafson Y, Schroll M, Hansen FR, Saare-la M, Nygaard H, et al. Geriatric rehabilitation as an
integral part of geriatric medicine in the Nordic coun-tries. Danish medical bulletin. 2003;50(4):439-45. Epub 2003/12/26.
Berrahmoune H, Lamont J, Fitzgerald P, Visvikis-Siest S. Inter-individual variation of inflammatory markers of cardiovascular risks and diseases. Clinical chemistry and laboratory medicine : CCLM / FESCC. 2005;43(7):671-84. Epub 2005/10/07.
Jee WS. Principles in bone physiology. Journal of muscu-loskeletal & neuronal interactions. 2000;1(1):11-3. Epub 2005/03/11.
Chanavaz M. Maxillary sinus: anatomy, physiology, sur-gery, and bone grafting related to implantology--elev-en years of surgical experience (1979-1990). The Jour-nal of oral implantology. 1990;16(3):199-209. Epub 1990/01/01.
Kasakura S. Great contributions of E. Donnall Thomas to the development of clinical applications of bone marrow transplantation, leading to the 1990 Nobel Prize in Med-icine/Physiology. International journal of hematology. 2005;81(2):87-8. Epub 2005/04/12.
Muller W. Bone physiology. 1926. Clinical orthopaedics and related research. 1990(258):3-8. Epub 1990/09/01.
Brookes M. Blood Supply of Long Bones. British medical journal. 1963;2(5364):1064-5. Epub 1963/10/26.
Fernandez-Tresguerres-Hernandez-Gil I, Alobera-Gracia MA, del-Canto-Pingarron M, Blanco-Jerez L. Physiologi-cal bases of bone regeneration I. Histology and physiolo-gy of bone tissue. Medicina oral, patologia oral y cirugia bucal. 2006;11(1):E47-51. Epub 2006/01/03.