Magnesium: How Can We Benefit?


  • Syed Hamid Habib Institute of Basic Medical Sciences, Khyber Medical University, Pakistan



Magnesium, Health


Magnesium is one of the important minerals that has multiple physiological roles. However, its role has not been valued and has remained one of the most underestimated micronutrient imbalance. This is one of the reason for its low intake, and being ignored by physicians and nutritionists. Magnesium is mostly found in intracellular spaces of the body, mainly in skeleton complexed with calcium and phosphorus and  also in soft tissues, muscles,  and other organs.1 Magnesium is involved in a variety of biochemical and metabolic processes such as neuromuscular functions, bone deposition, energy storage etc. It  also has role in the modification of intestinal microbiota and metabolism of different vitamins.


Piuri G, Zocchi M, Della Porta M, Ficara V, Manoni M, Zuccotti GV, Pinotti L, Maier JA, Cazzola R. Magnesium in Obesity, Metabolic Syndrome, and Type 2 Diabetes. Nutrients. 2021 Jan 22;13(2):320. doi: 10.3390/nu13020320. PMID: 33499378; PMCID: PMC7912442.

Bairoch A. The ENZYME database in 2000. Nucleic Acids Res. 2000 Jan 1;28(1):304-5. doi: 10.1093/nar/28.1.304. PMID: 10592255; PMCID: PMC102465.

Blaine J, Chonchol M, Levi M. Renal control of calcium, phosphate, and magnesium homeostasis. Clin J Am Soc Nephrol. 2015 Jul 7;10(7):1257-72. doi: 10.2215/CJN.09750913. Epub 2014 Oct 6. Erratum in: Clin J Am Soc Nephrol. 2015 Oct 7;10(10):1886-7. PMID: 25287933; PMCID: PMC4491294.

Cambray S, Ibarz M, Bermudez-Lopez M, Marti-Antonio M, Bozic M, Fernandez E, Valdivielso JM. Magnesium Levels Modify the Effect of Lipid Parameters on Carotid Intima Media Thickness. Nutrients. 2020 Aug 28;12(9):2631. doi: 10.3390/nu12092631. PMID: 32872319; PMCID: PMC7551902.

Găman MA, Dobrică EC, Cozma MA, Antonie NI, Stănescu AMA, Găman AM, Diaconu CC. Crosstalk of Magnesium and Serum Lipids in Dyslipidemia and Associated Disorders: A Systematic Review. Nutrients. 2021 Apr 22;13(5):1411. doi: 10.3390/nu13051411. PMID: 33922341; PMCID: PMC8146023.

Vanoni FO, Milani GP, Agostoni C, Treglia G, Faré PB, Camozzi P, Lava SAG, Bianchetti MG, Janett S. Magnesium Metabolism in Chronic Alcohol-Use Disorder: Meta-Analysis and Systematic Review. Nutrients. 2021 Jun 7;13(6):1959. doi: 10.3390/nu13061959. PMID: 34200366; PMCID: PMC8229336.

Zhan J, Wallace TC, Butts SJ, Cao S, Ansu V, Spence LA, Weaver CM, Gletsu-Miller N. Circulating Ionized Magnesium as a Measure of Supplement Bioavailability: Results from a Pilot Study for Randomized Clinical Trial. Nutrients. 2020 Apr 28;12(5):1245. doi: 10.3390/nu12051245. PMID: 32353962; PMCID: PMC7281967.

Van Laecke S, Van Biesen W. Hypomagnesaemia in kidney transplantation. Transplant Rev (Orlando). 2015 Jul;29(3):154-60. doi: 10.1016/j.trre.2015.05.002. Epub 2015 May 7. PMID: 26001746.




How to Cite

Habib, S. H. (2023). Magnesium: How Can We Benefit?. ADVANCES IN BASIC MEDICAL SCIENCES, 7(1).