Etiologies of Intussusception in Atypical Age Group and Their Need for Biopsy

How to Cite

Mohammad Imran, Ata ul Haq, Sajjad Ali, Arbab Farooq Ahmad, & Rehmat Ali Khan. (2022). Etiologies of Intussusception in Atypical Age Group and Their Need for Biopsy. Advances in Basic Medical Sciences, 6(1), 12–15.



Objective: To determine the etiologies of intussusception in the atypical pediatric age group and their need for biopsy.

Material and Methods:

This retrospective chart review was done in the Department of Pediatrics Surgery, Khyber teaching hospital, Peshawar from 1st January 2021 to 31st December 2021. 43 patients of either gender, aged between 2-10 years were included in the study with a diagnosis of intussusception confirmed with ultrasonography. Patients presenting at the typical age of 3 months to 24 months were excluded from the study. Age, sex, chief complaint, clinical manifestation, and sonographic findings were recorded. The exact etiology of intussusception was confirmed by histopathology or per-op findings. Data were analyzed using SPSS. Mean and standard deviation was used for quantitative data. Frequency and percentages were used for qualitative data.


The mean age of the patients was 3.9 years ±1 years. There were 26 male and 17 female patients with a male to female ratio of 1:0.6. Among 27 (62%) cases with identifiable pathologic lead point, lymphoma was the cause of intussusception in 13 patients (48%), Meckel’s diverticulum in 8 patients (29%), Henoch-Schönlein purpura in 3 patients (11%) and previous history of surgical procedures like laparotomy in 3 patients(11%).


Lymphoma remains the most common cause of intussusception in the atypical age group in Pediatrics surgery patients followed by Meckel’s diverticulum. We also suggest that every patient presenting with the diagnosis of intussusception at atypical age must undergo biopsy and histopathology to treat the etiology of intussusception.

Key Words:

Intussusception, Atypical age Group, Biopsy
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