THERAPY SUCCESS RATE WITH PEGYLATED INTERFERON/RIBAVIRIN TREATMENT OF RELAPSE AND NON-RESPONDER HEPATITIS C PATIENTS

Authors

  • Faiqa Fateen Institute of Basic Medical Sciences, Khyber Medical University, Peshawar
  • Muhammad Noaman Yousaf Mufti Mahmood Teaching Hospital. Dera Ismail Khan
  • Niamatullah Khan Institute of Basic Medical Sciences, Khyber Medical University, Peshawar
  • Faisal Nouman Mufti Mahmood Teaching Hospital. Dera Ismail Khan
  • Waheed Iqbal Institute of Basic Medical Sciences, Khyber Medical University, Peshawar
  • Sami Siraj Institute of Basic Medical Sciences, Khyber Medical University, Peshawar

References

Mühlberger N, Schwarzer R, Lettmeier B, Sroczynski G, Zeuzem S, Siebert U. HCV-related burden of disease in Europe: a systematic assessment of incidence, prevalence, morbidity, and mortality. BMC Public Health. 2009;9(1):34.

Re VL, Kostman J. Management of chronic hepatitis C. Postgraduate medical journal. 2005;81(956):376-82.

Sherman M, Shafran S, Burak K, Doucette K, Wong W, Girgrah N, et al. Management of chronic hepatitis B: consensus guidelines. Canadian Journal of gastroenterology. 2007;21(Suppl C):5C.

Zeuzem S, Buti M, Ferenci P, Sperl J, Horsmans Y, Cianciara J, et al. Efficacy of 24 weeks treatment with peginterferon alfa-2b plus ribavirin in patients with chronic hepatitis C infected with genotype 1 and low pretreatment viremia. Journal of hepatology. 2006;44(1):97-103.

Yu M-L, Dai C-Y, Huang J-F, Hou N-J, Lee L-P, Hsieh M-Y, et al. A randomised study of peginterferon and ribavirin for 16 versus 24 weeks in patients with genotype 2 chronic hepatitis C. Gut. 2007;56(4):553-9.

Ferreira SdC, Carneiro MdV, Souza FF, Teixeira AC, Villanova MG, Figueiredo JFdC, et al. Long-term follow-up of patients with chronic hepatitis C with sustained virologic response to interferon. Brazilian Journal of Infectious Diseases. 2010;14(4):330-4.

Patel K, Muir AJ, McHutchison JG. Diagnosis and treatment of chronic hepatitis C infection. Bmj. 2006;332(7548):1013-7.

Lindh M, Arnholm B, Eilard A, Farkkila M, Hellstrand K, Lagging M, et al. Hepatitis C treatment response kinetics and impact of baseline predictors. Journal of viral hepatitis. 2011;18(6):400-7.

Cariani E, Villa E, Rota C, Critelli R, Trenti T. Translating pharmacogenetics into clinical practice: interleukin (IL)28B and inosine triphosphatase (ITPA) polymophisms in hepatitis C virus (HCV) infection. Clinical chemistry and laboratory medicine : CCLM / FESCC. 2011;49(8):1247-56.

Qureshi MS, Iqbal M, Nomani AZ, Rasheed K. Time for change: conventional interferon regimes should not be the standard of care for management of Pakistani genotype-3 in chronic hepatitis C. Journal of the College of Physicians and Surgeons--Pakistan : JCPSP. 2014;24(1):70-2.

D'Souza R, Main J, Crossey M, Rosenberg W, Murray-Lyon IM, Hayward C, et al. Discontinuation of pegylated interferon plus ribavirin in patients who are not responding to therapy -- patients' views of early cessation of therapy. Alimentary pharmacology & therapeutics. 2005;21(1):43-7.

Umar M, Bilal M. Hepatitis C, A Mega Menace: A Pakistani Perspective. Journal of Pakistan Medical Students. 2012;2(2).

Jacobson IM, Gonzalez SA, Ahmed F, Lebovics E, Min AD, Bodenheimer HC, et al. A randomized trial of pegylated interferon α-2b plus ribavirin in the retreatment of chronic hepatitis C. The American journal of gastroenterology. 2005;100(11):2453-62.

Oze T, Hiramatsu N, Mita E, Akuta N, Sakamoto N, Nagano H, et al. A multicenter survey of re-treatment with pegylated interferon plus ribavirin combination therapy for patients with chronic hepatitis C in Japan. Hepatology research : the official journal of the Japan Society of Hepatology. 2013;43(1):35-43.

Lagging M, Rembeck K, Rauning Buhl M, Christensen P, Dalgard O, Farkkila M, et al. Retreatment with peg-interferon and ribavirin in patients with chronic hepatitis C virus genotype 2 or 3 infection with prior relapse. Scandinavian journal of gastroenterology. 2013;48(7):839-47.

Ohno O, Mizokami M, Wu R-R, Saleh MG, Ohba K-i, Orito E, et al. New hepatitis C virus (HCV) genotyping system that allows for identification of HCV genotypes 1a, 1b, 2a, 2b, 3a, 3b, 4, 5a, and 6a. Journal of clinical microbiology. 1997;35(1):201-7.

Yoshida EM, Sherman M, Bain VG, Cooper CL, Deschenes M, Marotta PJ, et al. Retreatment with pegylated interferon alpha-2a and ribavirin in patients with chronic hepatitis C who have relapsed or not responded to a first course of pegylated interferon-based therapy. Canadian Journal of Gastroenterology. 2009;23(3):180.

Morris Sherman M, Cooper CL, Mel Krajden M, MD10 RJB. Retreatment with pegylated interferon alpha-2a and ribavirin in patients with chronic hepatitis С who have relapsed or not responded to a first course of pegylated interferon-based therapy. Can J Gastroenterol. 2009;23(3).

Pessôa MG, Cheinquer H, Almeida PR, Silva GF, Lima MPJ, Paraná R, et al. R e-treatment of previous non-responders and relapsers to interferon plus ribavirin with peginterferon alfa-2a (40KD), ribavirin±amantadine in patients with chronic hepatitis C: randomized multicentre clinical trial. Ann Hepatol. 2012;11:52-61.

Dalgard O, Bjøro K, Hellum KB, Myrvang B, Ritland S, Skaug K, et al. Treatment with pegylated interferon and ribavarin in HCV infection with genotype 2 or 3 for 14 weeks: a pilot study. Hepatology. 2004;40(6):1260-5.

Niederau C, Mauss S, Schober A, Stoehr A, Zimmermann T, Waizmann M, et al. Predictive Factors for Sustained Virological Response after Treatment with Pegylated Interferon α-2a and Ribavirin in Patients Infected with HCV Genotypes 2 and 3. PloS one. 2014;9(9):e107592.

Davis GL, Wong JB, McHutchison JG, Manns MP, Harvey J, Albrecht J. Early virologic response to treatment with peginterferon alfaâ€2b plus ribavirin in patients with chronic hepatitis C. Hepatology. 2003;38(3):645-52.

Downloads

Published

2019-01-02

How to Cite

1.
Fateen F, Yousaf MN, Khan N, Nouman F, Iqbal W, Siraj S. THERAPY SUCCESS RATE WITH PEGYLATED INTERFERON/RIBAVIRIN TREATMENT OF RELAPSE AND NON-RESPONDER HEPATITIS C PATIENTS. Adv Basic Med Sci [Internet]. 2019Jan.2 [cited 2026Jan.18];1(1). Available from: https://abms.kmu.edu.pk/index.php/abms/article/view/2

Issue

Vol. 1 No. 1 (2017): Advances in Basic Medical Sciences

Section

Original Articles

License

Copyright (c) 2017 Faiqa Fateen, Muhammad Noaman Yousaf, Niamatullah Khan, Faisal Nouman, Waheed Iqbal, Sami Siraj

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Readers may Share-copy and redistribute the material in any medium or format and Adapt-remix, transform, and build upon the material. The readers must give appropriate credit to the source of the material and indicate if changes were made to the material. Readers may not use the material for commercial purpose. The readers may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.